Need to Know: The Wings' Michael Ryder scored the only goal in the shootout after Jacob Josefson, Michael Cammalleri, and Michael Ryder missed chances for the Devils and Pavel Datsyuk and Tomas Tatar failed to convert for Detroit.
Cammalleri had two goals, Jaromir Jagr a goal and assist, and Adam Henrique and Damon Severson had two assists. Henrique left the game for undisclosed reasons.
The Devils fell to 1-3 in shootouts and lost for the first time when leading after two periods (5-1-2).
The Red Wings outshot the Devils 17-6 in the second period, when they closed a three-goal deficit it one.
Cory Schneider made 15 saves in the period for the Devils and had 28 overall.
Jagr's goal gave him 709 for his career, surpassed Mike Gartner for sole possession of sixth on the all-time NHL list.
The Devils went 18 games without scoring four goals since scoring six and five, respectively, in their first two games. They've now done it twice in last three games.
Detroit has scored four or more goals 11 times in 2014-15 -- tied with Calgary for second most in the league (Tampa Bay has 11).
New Jersey allowed two power-play goals. In the previous seven they killed off 96.4 percent (27/28) of its opponents' extra-man chances -- best of any NHL club since Nov. 11.
Links: Box Score
What's Next: The Devils visit the Metropolitan Division co-leading Islanders Saturday at 7 p.m.