Giants center Jon Halapio was carted off the field with an air cast on his right leg in Sunday's game against the Dallas Cowboys in the third quarter.
Halapio, who earned the starting center job in training camp, got rolled up from behind on a run play. John Greco took over at center when play resumed.
The Giants are also playing without cornerback Eli Apple, who suffered a groin injury in the third quarter. BW Webb moved to the outside and Donte Deayon took over in the slot once Apple left the game.