Here is what you need to know....
Eli Manning returned to action yesterday after leaving practice early Wednesday with a stomach virus. He practiced with the first team and looked as if he never left. He says he is "100%" and ready for Sunday.
The only Giant to sit out of Thursday's practice was RB Ahmad Bradshaw (foot). He will practice today. Everyone else was suited up and working with the team. LB Mark Herzlich (ankle), DE Justin Tuck (shoulder), DE Osi Umenyiora (ankle, knee), CB Corey Webster (hamstring) were all limited. DB Deon Grant practiced with a brace on his arm.
RB Brandon Jacobs commented on Jerry Rice's assertion that he is "soft"....after Jacobs showered Rice with praise, he predicted: "I bet you he won't tackle me..."
49ers All-Pro LB Patrick Willis did not participate in practice yesterday due to a "previously undisclosed knee injury." CB Tarell Brown (thigh) also missed practice for the first time this week. C Jonathan Goodwin (left calf) and wide receiver/returner Ted Ginn (right knee) did not practice again and are questionable for Sunday.
The weather in San Francisco has not changed. It will rain straight through until Monday. Temperatures for gametime are expected to be around 60 degrees.
SNY Insider Mike Garafolo has more from TIMEX: