Need to know: Colin McDonald got the scoring started quickly in the first period to put the Islanders in front. Anders Lee and Mikhail Grabovski each added a goal in the second period to make it a 3-0 game.
The Sabres would add two goals of their own late in the second but were unable to tie the game up.
Travis Hamonic recorded two assists while Jaroslav Halak saved eight of the ten shots on goal for the Islanders.
What's next: The Islanders host the Oilers on Tuesday at 7 p.m.