RB Matt Forte (knee), C Jonotthan Harrison (hand), DT Ed Stinson (neck), and DE Muhammad Wilkerson (shoulder, foot) all missed practice on Thursday.
"I don't know if it is serious or not serious," Jets head coach Todd Bowles said, "but anytime someone doesn't practice, it's serious for me."
Forte rushed for a season-high 77 yards and two touchdowns in last Thursday's 34-21 win over the Bills.
CB Morris Claiborne (foot) and G Brian Winters (abdomen) participated on a limited basis.
QB Christian Hackenberg, who was a limited participant on Wednesday due to a finger issue, participated in full.
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It's encouraging that Winters and Claiborne returned to practice, albeit on a limited basis. Even with Mike Evans out, the Bucs have some good pass catchers on their roster. They also have the formidable Gerald McCoy inside, so the Jets need to be at full strength on the offensive line. Based on the last month or so, we can also probably expect Muhammad Wilkerson to be ready by gameday, especially with the long week. However, this doesn't sound too promising in terms of Forte's availability.
The Jets coped quite well when Forte missed a couple of games earlier in the year, though, winning both of them. The first of those saw Bilal Powell and Elijah McGuire each have their best game of the season against Jacksonville.
However, Powell got injured early on in the Browns game and the Jets were unable to get the running game going with McGuire getting all the second half reps. Powell has had durability issues in the past when he gets a starter's workload.
If Forte can't play, the Jets could perhaps opt to bring someone in as cover. They previously had Travaris Cadet in that role, but he won't be an option because he just signed with Buffalo.