Ideally, you'd like to force every player to the mid range area, seeing that players who specialize there are a commodity. In their only match up of the season, Pierce outperformed Melo on the offensive end when both were matched up together. Pierce is 4-6 vs 3-8 in the mid range area versus Melo. Also, down the stretch, overall Pierce looked to make passes when he was isolated, averaging 4 assists in the last 5 minutes of the game. Keep in mind about Melo that he posts up in the mid range area and uses his jump shots to set up drives to the basket.
What is obvious, or at least has been during the regular season match ups, is that Garnett enjoys the space Amar'e Stoudemire gives him when he is on the floor. The question becomes how often will STAT be guarding KG? If these numbers are any indication, you would hope not that many.
KG's huge advantage is his mid range jump shot. He's 7-foot and has a ridiculously high release. It's impossible to guard and he makes them like FTs. When Amar'e is on the floor he can't contest the jumper as the numbers say he shoots 67% from the mid range area and averages his most amount of points vs. Stoudemire. The defensive thinking has to be make KG put the ball on the floor by aggressively closing out. There has been talk of putting Jeffries on Rondo, but I believe Jeffries is better suited to guard KG when he is looking for his jump shot. Jeffries' length and competent footwork could be a good combination against Garnett.
Plenty of cool individual tendencies and match up stuff, some of which of course can be a bit misleading, but you can find and create your own keys to the series here.