Joakim Noah has been medically cleared by the NBA's independent doctor and will begin his 20-game suspension on Wednesday night, reports Ian Begley of ESPN.
Noah will miss the final eight games of this season and the first 12 of the 2017-18 season.
He said the substance that resulted in the suspension was not approved by the Knicks' medical staff and that he took it while rehabbing from an injury.
Noah, 32, averaged 5.0 points and 8.8 rebounds in 46 games this season while missing time due to knee, hamstring, and ankle injuries.
He signed a four-year deal with the Knicks worth $72.59 million prior to this season.