Granderson ran into the outfield fence in the first inning, tracking a fly ball. He stayed in the game for a few innings, even picking up an RBI single, but was later removed. The Mets said he has left rib cage, knee and forearm contusions. X-rays will be taken on Monday night.
Lagares grabbed his hamstring after beating out a double play in the seventh inning. He stayed in for a pitch before being removed. Lagares had a right hamstring strain, the Mets said.
Andrew Brown took over in right field for Granderson, and Lagares' injury forced Lucas Duda into left field, with Eric Young Jr. shifting over to center. Duda hadn't played in the outfield since June 2013.
Chris Young, who is rehabbing from injury in the minors, isn't eligible to return from the disabled list until April 18.