Manfred, 55, currently MLB's chief operating officer, was elected in a vote of the 30 clubs Thursday, the final day of the quarterly owners meetings in Baltimore. He was a finalist along with Red Sox chairman Tom Werner. MLB's executive vice president of business Tim Brosnan reportedly withdrew before the first vote.
The vote was unanimous. Werner also reportedly withdrew when it became apparent Manfred would have the 23 votes (75 percent) needed to win.
Selig's term ends Jan. 24. The former Milwaukee Brewers owner took over in 1992 after the firing of Fay Vincent. Two years later, baseball's ongoing labor trouble led to a strike that resulted in the cancellation of the postseason. Since 1995, Selig has been able to maintain labor peace while making significant changes such as interleague play and expanded playoffs.
Revenues and attendance improved during Selig's tenure, which included the construction of many new ballparks, including two in New York. Selig was criticized by some for a slow response to the use of performance-enhancing drugs, but played a role in developing the program that tests and penalizes players for using them.
Manfred, who lives in Rye, N.Y., will be the 10th Commissioner in MLB history. He served MLB as an outside counsel during the 1994 strike, joined MLB on a full-time basis in 1998 and became COO in September 2013. That position had been vacant since 2010, when Bob DuPuy was fired.