The Mets and Yankees played their first regular season series in 1997 at Yankee Stadium as interleague play debuted throughout Major League Baseball.
Since then, there have been tons of memorable moments for the Mets as Queens has battled the Bronx.
Here are the top five...
5.) Dae-Sung Koo's double and dash: May 21, 2005
Mr. Koo, as he was affectionately known, was a lefty specialist who spent one year in the majors. That included ripping a double to the warning track off Randy Johnson at Shea Stadium during the Mets' 7-1 win. After the double, Koo scored on a bunt. Yes, a bunt.
4.) Dave Mlicki's shutout: June 16, 1997
In the first-ever Subway Series game, Mlicki tossed a shutout at Yankee Stadium as the Mets won, 6-0, capping the night with an emphatic scream from the mound after striking out Derek Jeter for the final out.
3.) David Wright wins it against Mariano Rivera: May 19, 2006
After rallying from an early four-run deficit, Wright hit a double off Rivera in the ninth inning at Shea Stadium to give the Mets a 7-6 win, with the ball going over the head of Yankees center fielder Johnny Damon.
2.) Mike Piazza hits a grand slam against Roger Clemens: June 9, 2000
Piazza owned Clemens during their careers, and part of that dominance manifested itself when Piazza crushed a grand slam off Clemens at Yankee Stadium during the Mets' 12-2 victory. Clemens couldn't handle being owned by Piazza, and drilled him in the head with a fastball during the teams' next series on July 8. He then threw part of Piazza's shattered bat directly at Piazza during Game 2 of the 2000 World Series at Yankee Stadium and was somehow not ejected for it.
1.) Matt Franco wins it against Mariano Rivera: July 10, 1999
In a wild back-and-forth game at Shea Stadium, Franco's pinch-hit, two-out, two-strike single off Rivera in the bottom of the ninth inning brought in the tying and winning runs in the Mets' 9-8 victory.