The Mets have placed Wilmer Flores (knee infection) and Lucas Duda (hyperextended elbow) to the 10-day disabled list, the team announced Friday.
Flores, who spent Wednesday night in the hospital, will remain in the hospital throughout the weekend to receive IV fluids.
T.J. Rivera, who is in Friday night's lineup at third base, and Sean Gilmartin have been called up from Triple-A Las Vegas.
Duda had been unavailable since injuring his elbow during Wednesday's game, resulting in Jay Bruce getting the start Thursday and Friday at first base.
Flores is hitting .171 with a .194 OBP and .343 SLG with two HR and three RBI this season.
Duda is hitting .238 with a .360 OBP and .571 SLG with four homers and seven RBI.