It will be the third meeting of the season for the two Atlantic division rivals, with each team winning a memorable game at home against one another back in December.
The Nets scored a season-high 130 points against Philly on December 16, with Joe Johnson tying an NBA record with eight of his 10 three-pointers in a 29-point third quarter, as the Nets set a franchise record with 21 made three-pointers.
A few days later, the 76ers got their revenge, as they beat Brooklyn on a buzzer-beater by Evan Turner in the game that the Nets lost Brook Lopez for the season.
Philly had won six straight on the Nets' home floor before the Nets' move to Brooklyn, but the Sixers have not won a single game at the Barclays Center in three tries since the move. Philadelphia leads the all-time series 102-72, and are 45-42 on the Nets' home court all-time. Brooklyn's 130-94 victory in December was the largest margin of victory for either team in the rivalry's history.
This season, the Sixers have struggled, with a 15-33 record that puts him dead last in the Atlantic entering tonight, with the third-worst overall record in the Eastern Conference.
Nevertheless, Philadelphia has a trio of players averaging over 17 points per game in Evan Turner, Thaddeus Young, and rookie sensation Michael Carter-Williams.
Key Matchup: Turner was the thorn in the Nets' side in Philadelphia's 121-120 victory the last time these two teams squared off, as he scored a game-high 29 points with 10 rebounds, including the game-winner at the buzzer to stun the visiting Nets.
The Nets may use the length of Shaun Livingston on Turner tonight, with one of their key defenders, Andrei Kirelenko, doubtful for tonight's game with a calf injury.
Player to Watch: Deron Williams has struggled during the Nets' three-game losing streak, and this may be the type of game that can help him get back on track. Williams' two best games assists-wise were against Philly this year, as he had a season-high 14 assists in their road loss and 13 assists in their home victory.