Matt Holliday and Starlin Castro will begin rehab assignments on Friday, reports Bryan Hoch of MLB.com.
Holliday will play for Single-A Tampa, while Castro will play for Triple-A Scranton/Wilkes-Barre.
Prior to Monday's game against the Mets, Holliday took batting practice while Castro fielded grounders.
Holliday, who has been sidelined since Aug. 4 with a lower back strain, is hitting .229/.319/.430 with 16 home runs and 51 RBIs this season. Castro is working his way back from a hamstring injury, which landed him on the disabled list twice in the month of July. He last played for the Yankees on July 21.
Castro has a .307/.344/.472 batting line with 12 home runs and 45 RBIs in 79 games this season.